A 3rd efficient weapon was added to America’s arsenal towards the coronavirus on Saturday when the Food and Drug Administration granted emergency use authorization for a vaccine developed by Johnson & Johnson.
The firm mentioned it might begin delivery tens of millions of doses early this week, and would offer the United States with 100 million doses by the top of June. Together with 600 million doses of the nation’s first two approved vaccines, made by Pfizer-BioNTech and Moderna, which are on account of be delivered over the following 4 months, that must be sufficient to cowl each American grownup who desires to be vaccinated.
The new vaccine differs markedly from the 2 already in use within the United States. Here is how they evaluate.
One shot as a substitute of two
The Johnson & Johnson vaccine is run in a single shot, whereas the Pfizer-BioNTech and Moderna vaccines are given in two pictures a number of weeks aside.
The means it really works
The Johnson & Johnson vaccine makes use of a special methodology to prime the physique to struggle off Covid-19: a viral vector known as Ad26. Viral vectors are frequent viruses which have been genetically altered in order that they don’t trigger sickness however can nonetheless trigger the immune system to construct up its defenses. The Pfizer-BioNTech and Moderna vaccines use messenger RNA to do this.
How effectively it really works
The Johnson & Johnson vaccine is rated as extremely efficient at stopping critical sickness and demise, because the Pfizer-BioNTech and Moderna vaccines are. It can be very efficient at stopping milder sickness, although a bit much less so than these two. It seems to do effectively towards the extremely contagious B.1.351 variant, first recognized in South Africa, that has given not less than one different vaccine candidate bother.
Storage and dealing with
The Johnson & Johnson vaccine doesn’t need to be saved at extraordinarily low temperatures just like the Pfizer-BioNTech vaccine. It can safely be stored in an odd fridge for 3 months, for much longer than the Moderna vaccine, which spoils after a month if not stored frozen.
The Johnson & Johnson vaccine seems to be much less inclined than the Pfizer-BioNTech and Moderna vaccines to set off the sorts of uncomfortable side effects that require monitoring after the injection, which can make it extra appropriate to be used at drive-through vaccination websites. There have been experiences that uncomfortable side effects are typically felt extra strongly after second doses, which the Johnson & Johnson vaccine doesn’t require.